NMN Supplement and Aging

Oct 06, 2023

By Dr. Sean Wells, DPT, PT, OCS, ATC/L, CSCS, NSCA-CPT, CNPT, Cert-DN

Nicotinamide mononucleotide (NMN) is a molecule that has gained attention in recent years due to its potential role in enhancing longevity and healthspan. Doctors of Physical Therapy (DPTs) ought to be aware of NMN as many clients have begun taking them and are unaware of new data and legal challenges ahead. NMN is a precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme involved in various cellular processes, including energy metabolism and DNA repair. Research on NMN supplementation in humans is ongoing, and while there is some promising evidence, it's important to note that the field is still evolving, and more research is needed to draw definitive conclusions.
Here is a research summary of NMN use in humans up to my knowledge cutoff date in September 2021:

  1. NAD+ Levels: One of the primary reasons for interest in NMN is its potential to boost NAD+ levels in cells. NAD+ declines with age, and...
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Rhodiola Rosea: A Physical Therapist’s Tool or Gimmick?

Nov 17, 2022

Rhodiola Rosea: A Physical Therapist’s Tool or Gimmick?

By Dr. Sean M. Wells, DPT, PT, OCS, CNPT, ATC/L, CSCS, NSCA-CPT, Cert-DN

Many patients in my practice come to me asking how they can get more energy for their daily activities. Of course, being a holistic physical therapist I talk with them about sleep hygiene, scheduling, daily aerobic exercise, and nutrition. While many of these interventions help significantly, some of my patients with autoimmune disorders often still struggle with energy and fatigue. I also have a subset of patients in my practice that simply just want more performance for their daily activities as well as for sports. Both of these groups of patients are willing to try almost any dietary supplement, which can be both good and bad: The willingness to try new things is good but many supplements are not regulated and can interact with drugs or cause severe Adverse Events.  

Recently I was listening to the Huberman Podcast and Dr Layne Norton...

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Best Nutrition Guide for PTs

Apr 08, 2022

By Dr. Sean M. Wells, DPT, PT, OCS, CNPT, ATC/L, CSCS, NSCA-CPT, Cert-DN

Physical therapists (PTs) are direct care providers who help people across many settings and with various pathologies and functional losses. From cardiac issues, metabolic dysfunction, cancer, neurological deficits, and musculoskeletal disorders, PTs can help a variety of patients get stronger, move with more confidence, and feel better. One key tool that can help with PT's treatments is nutrition.

Nutrition is in the scope of practice of Doctors of PT (DPTs), according to the American Physical Therapy Association (APTA). Nutrition is linked with inflammation, recovery, pain, psychological well being, and quality of life. Plus, most of our clients are taking supplements or simply want to get better, faster with any approach possible -- as such, PTs need more quality dietary info.

One of the best evidenced-based resources for nutrition is Examine.com. Examine offers copious research, great summaries, and...

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COVID, Vitamin D, and Physical Therapy

Jan 04, 2021

Emerging evidence is revealing how Vitamin D can help patients with COVID-19, commonly known as the Coronavirus.  Vitamin D is known as the "sunshine vitamin" as it is produced in the skin with sun exposure. Most Americans are deficient in Vitamin D, possibly due to the lack of optimal sun exposure and/or their poor diets. In order to get peak Vitamin D levels from sun exposure, a person must remain in direct sun with most the body exposed for 20 minutes under peak sun (usually 11am to 1pm). Vitamin D can be found as a fortification in many foods such as cereals, dairy milk, plant-based milks, while it is found naturally in some mushrooms. The specific Vitamin D in focus would be D3, also known as cholecalciferol.

So what's the data on Vitamin D and COVID-19? Well, randomized trials and cross sectional studies have shown that ~60% of patients with COVID-19 were vitamin D deficient upon hospitalization, with men in the advanced stages of COVID-19 pneumonia showing the greatest...

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