By Dr. Sean Wells, DPT, PT, OCS, ATC/L, CSCS, NSCA-CPT, CNPT, Cert-DN

Nicotinamide mononucleotide (NMN) is a molecule that has gained attention in recent years due to its potential role in enhancing longevity and healthspan. Doctors of Physical Therapy (DPTs) ought to be aware of NMN as many clients have begun taking them and are unaware of new data and legal challenges ahead. NMN is a precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme involved in various cellular processes, including energy metabolism and DNA repair. Research on NMN supplementation in humans is ongoing, and while there is some promising evidence, it's important to note that the field is still evolving, and more research is needed to draw definitive conclusions.
Here is a research summary of NMN use in humans up to my knowledge cutoff date in September 2021:

1. NAD+ Levels: One of the primary reasons for interest in NMN is its potential to boost NAD+ levels in cells. NAD+ declines with age, and maintaini
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